Rhodiola Rosea is a flowering plant in the family Crassulaceae, native to cold climates primarily in the Central Asian mountains.
The active ingredients in Rhodiola Rosea are rosavins and salidroside.
Rosavin is a cinnamyl alcohol glycoside.
Salidroside (Rhodioloside) is a glucoside of tyrosol.
Rhodiola Rosea may act as a mild monoamine oxidase inhibitor (MAOI), which inhibits breakdown of monoamines such as epinephrine, norepinephrine, and dopamine. This has been shown to help with stress and cognition.
Rhodiola Rosea was associated with decreased fatigue in a group of healthy physicians working night shifts.
Rhodiola rosea has been shown to decrease fatigue in 161 military cadets, as shown by the Total Antifatigue Index.
Rhodiola Rosea has been shown to decrease fatigue in healthy participants, as measured by the Pines burnout scale, the Conners' computerized continuous performance test II (CCCPT II) indices and the Hit RT SE.
Rhodiola Rosea has been shown to increase attention and decrease self-reported stress-related fatigue in college students taking it daily over 20 days before final exams. There were improvements in tests for neuromotoric fitness (maze test, tapping test), mental capacity (correction test), general well-being (emotional state and motivation as measured by the SAM questionnaire).
Rhodiola rosea taken one hour before physical activity has been shown to improve attention in healthy individuals, as measured by the Fepsy Vigilance test.
Rhodiola rosea has not been shown to have addiction or withdrawal effects.
Rhodiola rosea has been associated with mild hypersalivation.
Rhodiola rosea has been associated with increased sensitivity, anxiety, irritability, insomnia, headache, and rarely palpitations.
Rhodiola Rosea is approved as a dietary supplement component under provisions of the Dietary Supplement Health and Education Act of 1994. It is classified as generally recognized as safe (GRAS).